Prostaglandin levels and platelet function typically recover within 1–2 days after discontinuing Toradol (ketorolac). Most drug effects subside quickly, but serious complications like GI or kidney injuries may persist if they occur.
Prostaglandin levels—specifically those associated with platelet function and gastrointestinal protection—recover relatively quickly after discontinuing Toradol (ketorolac):
Platelet function: Inhibition of platelet aggregation caused by ketorolac is reversible, and platelet function typically returns to normal within 24–48 hours after discontinuation.
General prostaglandin-mediated effects: While direct data on the timing of full prostaglandin level recovery are limited, clinical effects (such as GI mucosal protection and renal function) generally begin to normalize within a few days after stopping the medication, assuming no underlying complications or chronic damage has occurred.
Drug elimination: The half-life of ketorolac is about 5–6 hours in healthy adults, so most of the drug is cleared within 1–2 days, supporting rapid recovery of prostaglandin synthesis pathways.
In summary: Prostaglandin synthesis and its effects (especially on platelets) typically recover within 1–2 days after Toradol is discontinued. However, some serious adverse effects (such as GI injuries or renal damage) may persist longer if they occur.
