Avoid Sandostatin LAR syringe clogs by letting vials reach room temp, fully saturating the powder, shaking thoroughly, and injecting promptly. Proper reconstitution and technique ensure smooth administration and prevent blockages.
The primary ways that can cause clogging of the Sandostatin LAR syringe are related to preparation and handling errors during reconstitution and injection:
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Insufficient vial shaking can cause incomplete reconstitution and syringe clogging.
Not allowing the injection kit and vial to reach room temperature before reconstitution. The kit should stand at room temperature for at least 30 minutes before use.
Inadequate saturation of the powder with the diluent solution after adding the diluent. The vial must stand for a minimum of 2 minutes and up to 5 minutes to ensure full saturation.
Insufficient shaking of the vial to form a uniform suspension. The vial must be shaken moderately in a horizontal direction for at least 30 seconds, and repeated if the powder is not fully suspended. Failure to do this can lead to incomplete reconstitution and syringe clogging.
Delays between preparation and injection causing sedimentation of the suspension, which may clog the needle.
Additional recommendations include pushing the plunger all the way down after reconstitution and using a proper 19-gauge needle for injection. If the needle clogs during injection, replacing the needle is advised.
Kevin Van, PharmD, BCPS (Editor)